EXamining ouTcomEs in chroNic Disease in the 45 and Up Study (EXTEND45)

The existing 45 And Up Study was a large-scale cohort study that recruited more than 250,000 NSW residents aged 45 years and older (representing 10% of the population in that age bracket), asking participants a range of questions relating to their health, lifestyle, and family/social support. The study provided researchers with a unique canvas on which to examine healthy ageing and chronic diseases at a population level.

The EXTEND45 study expands on the original dataset by linking 45 And Up results with diagnostic testing data from private pathology companies, along with data held in administrative datasets such as the Medicare Benefits Schedule/Pharmaceutical Benefits Scheme (MBS/PBS), the Australian Bureau of Statistics (ABS), and several more.

This linking of information, performed  via best practice methodologies at the Centre for Health Record Linkage (CHeReL) and under strict confidentiality and privacy guidelines, will allow us to examine the complete disease pathway for people with diabetes and Chronic Kidney Disease (CKD). It is hoped that this rich and detailed snapshot of the NSW population will thus allow researchers a fundamental insight into planning for the prevention and management of complex chronic diseases, and allow us to narrow the gap between evidence and clinical practice.