02199nas a2200229 4500000000100000008004100001100001400042700002000056700001900076700001600095700002500111700001800136700001400154700001600168700002000184700002000204700001900224700001800243245007400261520162000335022001401955 2017 d1 aMyburgh J1 aGillies Michael1 aSander Michael1 aShaw Andrew1 aWijeysundera Duminda1 aAldecoa Cesar1 aJammer Ib1 aLobo Suzana1 aPritchard Naomi1 aGrocott Michael1 aSchultz Marcus1 aPearse Rupert00aCurrent research priorities in perioperative intensive care medicine.3 a

INTRODUCTION: Surgical treatments are offered to more patients than ever before, and increasingly to older patients with chronic disease. High-risk patients frequently require critical care either in the immediate postoperative period or after developing complications. The purpose of this review was to identify and prioritise themes for future research in perioperative intensive care medicine.

METHODS: We undertook a priority setting process (PSP). A panel was convened, drawn from experts representing a wide geographical area, plus a patient representative. The panel was asked to suggest and prioritise key uncertainties and future research questions in the field of perioperative intensive care through a modified Delphi process. Clinical trial registries were searched for on-going research. A proposed "Population, Intervention, Comparator, Outcome" (PICO) structure for each question was provided.

RESULTS: Ten key uncertainties and future areas of research were identified as priorities and ranked. Appropriate intravenous fluid and blood component therapy, use of critical care resources, prevention of delirium and respiratory management featured prominently.

CONCLUSION: Admissions following surgery contribute a substantial proportion of critical care workload. Studies aimed at improving care in this group could have a large impact on patient-centred outcomes and optimum use of healthcare resources. In particular, the optimum use of critical care resources in this group is an area that requires urgent research.

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