01888nas a2200193   4500000000100000008004100001100001400042700001600056700001400072700001700086700002000103700001300123700001400136700001900150245009300169250002000262520136600282020004601648       2012                            d1 aCarter G.1 aCrimmins D.1 aClarke T.1 aArblaster L.1 aMysore Jayanthi1 aSturm J.1 aHackett M1 aBillot Laurent00aImProving Outcomes after STroke (POST): results from the randomized clinical pilot trial  a2012 October 183 a<p>
BACKGROUND: One in three patients experience depression after stroke. An effective strategy to prevent depression after stroke that could be economically delivered to most patients with a low likelihood of adverse events is needed. METHODS: In a randomized trial conducted in New South Wales, Australia, a postcard was sent monthly to participants (n = 100) for five-months following hospital discharge after stroke (plus usual care) and compared with usual care (n = 101). Ethical approval was obtained to withhold information about the intervention and primary outcome from participants during the consent process. RESULTS: No significant difference was seen in the proportion of participants with depression in the intervention group (1/88) vs. the control group (3/76) (relative risk 0.29, 95% confidence interval 0.03-2.71) at six-months. No significant differences were seen on Hospital Anxiety Depression Scale (HADS) depression and anxiety sub-scale scores, quality of life, or activities of daily living; however, many (47/100) responded positively to the postcards. CONCLUSIONS: Although this simple postcard intervention did not significantly reduce the proportion of participants experiencing high HADS depression sub-scale scores after stroke, it may be an effective way to engage with people after stroke following hospital discharge.
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