00411nas a2200169   4500000000100000008004100001100005000042700001600092700001900108700001500127700001800142700001500160245004300175300000900218490000800227050000600235       2008                            d1 aADVANCE Collaborative Group Writing Committee1 aChalmers J.1 aBillot Laurent1 aNeal Bruce1 aPatel Anushka1 aMacmahon S00aThe ADVANCE trial – Author’s reply  a26. 0 v371  aY